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GENE THERAPY

At the forefront of medicine, Gene Therapy brings you the latest research into genetic and cell-based technologies to treat disease. It also publishes Progress & Prospects reviews and News and Commentary articles, which highlight the cutting edge of the field.

Gene Therapy Development of an enhanced B-specific lentiviral vector expressing BTK: a tool for gene therapy of XLA Wild-type adenoviruses from groups A?F evoke unique innate immune responses, of which HAd3 and SAd23 are partially complement dependent Improved lentiviral vectors for Wiskott?Aldrich syndrome gene therapy mimic endogenous expression profiles throughout haematopoiesis Characterization of the adaptive and innate immune response to intravenous oncolytic reovirus (Dearing type 3) during a phase I clinical trial RNA-loaded CD40-activated B cells stimulate antigen-specific T-cell responses in dogs with spontaneous lymphoma AAV?BDNF mediated attenuation of quinolinic acid-induced neuropathology and motor function impairment Atelocollagen-mediated local and systemic applications of myostatin-targeting siRNA increase skeletal muscle mass Connective tissue growth factor linked to the E7 tumor antigen generates potent antitumor immune responses mediated by an antiapoptotic mechanism Adenovirus targeting to HLA-A1/MAGE-A1-positive tumor cells by fusing a single-chain T-cell receptor with minor capsid protein IX Baculovirus-mediated interferon alleviates dimethylnitrosamine-induced liver cirrhosis symptoms in a murine model Heat shock protein inhibitors increase the efficacy of measles virotherapy Site-specific gene modification by oligodeoxynucleotides in mouse bone marrow-derived mesenchymal stem cells Targeting gene expression to cones with human cone opsin promoters in recombinant AAV Repopulation of B-lymphocytes with restricted gene expression using haematopoietic stem cells engineered with lentiviral vectors Absence of retroviral vector-mediated transformation of gene-modified T cells after long-term engraftment in mice Clickbank Content Work From Home